Expanding the Therapeutic Window for Immune- Engaging Multi-Specifics Through Conditional Activation & Co-Stimulation

Time: 2:15 pm
day: Track A - Day 1 PM


  • ProTECT™ platform to engineer conditionally-active antibodies combined with checkpoint modulation to enhance therapeutic windows
  • Mechanistic validation and in vivo demonstration of enhanced potency for a proof-of-concept CD3-redirecting multispecific with PD-L1 modulation